Important: Compounded semaglutide and tirzepatide are not approved finished drug products. Pricing and availability are subject to clinical appropriateness and regulatory change. Prescriptions are issued only when an independent licensed medical provider determines individual clinical appropriateness. Read full consent →
Compounded semaglutide starting at $249/month and tirzepatide starting at $339/month through Open Water Rx. Each plan covers clinician review, medication if prescribed, shipping if prescribed, and ongoing support. No separate medication charge. Serving Los Angeles, San Diego, San Jose, San Francisco, Sacramento, Fresno, and all of California.
Semaglutide
$249/mo
Tirzepatide
$339/mo
No commitment required · No insurance required · Serving all of California
Direct Answer
Through Open Water Rx, compounded semaglutide starts at $249/month and compounded tirzepatide starts at $339/month across all of California, including Los Angeles, San Diego, San Jose, San Francisco, Sacramento, Fresno and every other city and zip code. Each price is all-inclusive: clinician review, medication if prescribed, shipping if prescribed, and ongoing async support. No insurance required. No separate medication charge. No hidden fees. From the entertainment capital of Los Angeles to the innovation hub of Silicon Valley and the Central Valley agricultural heartland, Californians statewide can access affordable GLP-1 weight loss care entirely online. Availability varies by state.
All-Inclusive Pricing
Provider review
A licensed medical provider reviews your case after submission.
Prescription if approved
Personalized prescription issued through a licensed compounding pharmacy.
Shipping included if prescribed
If medication is prescribed, it ships directly to your address at no extra charge.
Ongoing async follow-up
Secure provider messaging and scheduled check-ins throughout your program.
Base labs when appropriate
Baseline lab work included when clinically appropriate at your provider's discretion.
Transparent pricing
No setup fee, no consultation fee, no cancellation fee. Cancel anytime.
Cost Comparison
| Option | Monthly Cost |
|---|---|
Compounded Semaglutide (Open Water Rx) Open Water Rx | $249 |
Compounded Tirzepatide (Open Water Rx) Open Water Rx | $339 |
Wegovy® (retail pharmacy, no insurance) | ~$1,300 |
Ozempic® (retail pharmacy, no insurance) | ~$900 |
Zepbound (retail pharmacy, no insurance) | ~$1,000 |
FAQ
Through Open Water Rx, compounded semaglutide starts at $249/month. This price covers clinician review, compounded semaglutide if prescribed, shipping if prescribed, and ongoing async support. No separate medication charge.
Through Open Water Rx, compounded tirzepatide starts at $339/month. This price covers clinician review, compounded tirzepatide if prescribed, shipping if prescribed, and ongoing async support. No separate medication charge.
Retail Wegovy® costs approximately $1,300/month and Ozempic® approximately $900/month without insurance. Compounded semaglutide is prepared by independent, licensed compounding pharmacies using the base active pharmaceutical ingredient (API), which is significantly less expensive than the branded finished drug product. The cost difference reflects the absence of brand-name markup, not a difference in the active ingredient itself. Compounded semaglutide is not an approved finished drug product and is not the same as or interchangeable with any commercially approved product.
Most insurance plans do not cover GLP-1 medications prescribed solely for weight loss. Coverage for type 2 diabetes indications varies by plan. Open Water Rx does not accept insurance. Pricing is clear from the start: semaglutide starting at $249/month, tirzepatide starting at $339/month. No prior authorizations, no insurance battles.
Both plans include: clinician review by a licensed medical provider, compounded medication if prescribed, shipping if prescribed, and ongoing async support including secure patient messaging. No separate medication charge. Pricing is clear from the start with no hidden fees.
Yes. Some longer-term prepaid plans may lower the effective monthly rate compared to month-to-month pricing. Details are provided during the enrollment process. There is no obligation to commit to a longer plan.
No. There is no separate consultation fee, setup fee, or enrollment fee. The monthly plan price covers clinician review, medication if prescribed, and shipping if prescribed. If a prescription is not issued following your evaluation, a refund may be considered on a case-by-case basis at our discretion.
Open Water Rx pricing is competitive with or lower than major national GLP-1 telehealth platforms, with the added benefit of licensed medical providers, shipping included in the plan price if prescribed, and direct provider access. National platforms may charge separately for consultations, shipping, or medication. Always compare total all-in monthly cost.
In 2026, compounded semaglutide through Open Water Rx starts at $249/month across all of California, covering clinician review, medication if prescribed, shipping if prescribed, and ongoing async support. Compounded tirzepatide starts at $339/month on the same basis. Both are significantly lower than retail brand-name GLP-1 pricing. Serving Los Angeles, San Diego, San Jose, San Francisco, Sacramento, Fresno and every other city and zip code in California.
Get started today. Semaglutide starting at $249/month, tirzepatide starting at $339/month. Clear pricing from the start. No commitment required.
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