Medical Weight Loss Programs Online
Compounded semaglutide and tirzepatide programs reviewed by independent licensed providers. No waiting rooms, no insurance required, no guesswork. If clinically appropriate, care ships discreetly to you.
Treatment is determined by independent licensed providers. Not all patients qualify. Availability varies by state. Medication is prescribed only when clinically appropriate.
Important FDA Notice: Compounded semaglutide and tirzepatide are not FDA-approved finished drug products. All prescribing decisions are made by independent licensed medical providers. A valid patient-provider relationship must be established before any prescription is issued. Open Water Rx does not manufacture, compound, or dispense medications. Read full consent →
How It Works
Care that starts at home.
No waiting rooms. No insurance battles. A licensed provider reviews every case — and prescribes only when clinically appropriate.
Start from home
Complete your online intake in minutes. Available 24/7 from any device. No appointment needed.
Provider-reviewed
An independent licensed provider reviews your health history and determines if treatment is clinically appropriate.
Discreet treatment
If prescribed, medication ships discreetly from a licensed pharmacy partner directly to your door.
Transparent Pricing
Know the cost before you start. No hidden fees.
Open Water Rx is built around clear, upfront pricing. Review program costs before you begin, with no insurance required and no surprise charges hidden behind the intake.
Clear program pricing
See starting costs before you commit.
No insurance required
Cash-pay programs with transparent pricing.
No surprise add-ons
Provider review, support, and shipping details are clearly explained.
The Open Water Rx Difference
Care that fits your life —
not the other way around.
Entirely online. No waiting rooms. No insurance battles. From intake to delivery, everything happens from home.
Treatment Options
Two medications. One goal.
Both are clinician-reviewed and prescribed only when appropriate. Your licensed provider recommends the right option based on your health profile. Compare semaglutide and tirzepatide side by side →
Interested in oral GLP-1 options without injections? Or prefer a personalized dosing approach? Your provider can guide you during your intake.
Semaglutide
GLP-1 receptor agonist
- 15–17% avg. body weight loss (STEP 1 trial)
- Weekly subcutaneous injection
- Oral/sublingual option when appropriate
- Clinician-reviewed dosing & titration
- Shipping included if prescribed
Tirzepatide
Dual GIP + GLP-1 receptor agonist
- 20–22% avg. body weight loss (SURMOUNT-1 trial)
- Highest weight loss in any pharma trial
- Weekly subcutaneous injection
- Clinician-reviewed dosing & titration
- Shipping included if prescribed
Final treatment decisions are made by an independent licensed provider. Not all patients qualify. Compounded medications are not FDA-approved finished drug products.
Personalized GLP-1 Dosing Options
Some patients may be interested in lower-dose GLP-1 treatment based on tolerability, goals, or provider guidance. Dosing decisions are made by an independent licensed provider after reviewing your health history, medications, and risk factors.
What personalized dosing may include
- Lower starting doses for improved tolerability
- Slower titration schedules based on your response
- Provider-guided adjustments throughout your program
- Ongoing monitoring and follow-up included
Lower-dose GLP-1 treatment may be considered when clinically appropriate. It is not suitable for everyone, and results vary.
Eligibility
Is this right for me?
Eligibility is always determined by an independent licensed provider based on your individual health profile. This is a general guide only.
May be considered for
- Adults seeking clinician-guided weight loss support
- People who have struggled with diet and exercise alone
- Patients seeking private, fully online care
- BMI 30+ or BMI 27+ with a weight-related condition
- Those managing weight-related health conditions
May not be appropriate for
- Pregnant or breastfeeding patients
- Certain endocrine cancer history (MTC, MEN2)
- Contraindications determined by provider review
- Patients under 18 years of age
- Those with conditions that preclude GLP-1 use
Why Open Water Rx
Built around provider review,
not shortcuts.
Getting access to clinically appropriate weight loss care shouldn't require a waiting room, an insurance battle, or a $1,500/month brand-name prescription.
Secure intake
Your health information is encrypted and handled in strict accordance with HIPAA privacy standards. Never sold.
Independent licensed provider review
Every case is reviewed by a real licensed medical provider — not an algorithm. Clinical decisions are theirs alone.
Transparent pricing
Semaglutide from $249/mo. Tirzepatide from $339/mo. Everything disclosed before you pay. No hidden fees.
Clear safety information
We don't hide the compliance language. You deserve to know exactly what compounded medications are and aren't.
Discreet shipping if prescribed
Medication ships in plain, unmarked packaging from a licensed pharmacy partner. Shipping included in your program price.
Ongoing support
Ongoing provider follow-up, dose adjustments, and secure messaging included depending on program structure.
15–17%
Avg. weight loss with semaglutide
STEP 1 trial, NEJM 2021
20–22%
Avg. weight loss with tirzepatide
SURMOUNT-1 trial, NEJM 2022
All 50
States served nationwide
Availability varies by state
FAQ
Weight Loss Questions Answered
Semaglutide is a GLP-1 receptor agonist that works by slowing gastric emptying, reducing appetite, and improving insulin sensitivity. Tirzepatide is a dual GIP/GLP-1 receptor agonist — it targets two incretin pathways simultaneously, which generally produces stronger appetite suppression and greater average weight loss. In clinical trials, semaglutide averaged 15–17% body weight reduction; tirzepatide averaged 20–22%. Your licensed provider will recommend the most appropriate option based on your individual health profile.
The active pharmaceutical ingredients (semaglutide, tirzepatide) are FDA-approved in brand-name form. However, the compounded formulations dispensed through Open Water Rx's pharmacy partners are compounded medications — not FDA-approved finished drug products. They are prepared by licensed, FDA-registered compounding pharmacies for individual patients when a licensed provider determines there is a valid clinical reason.
Eligibility is determined by an independent licensed medical provider based on your individual health profile. Generally, GLP-1 programs are appropriate for adults with a BMI of 30+ (obese), or 27+ (overweight) with at least one weight-related health condition. A licensed provider reviews every case and prescribes only when clinically appropriate. Not all patients qualify.
Compounded semaglutide programs start from $249/month. Compounded tirzepatide programs start from $339/month. Pricing includes the medication, provider review, and shipping when prescribed. There are no hidden fees. Everything is disclosed before you pay.
No. Open Water Rx is a fully online telehealth platform. In most cases, no in-person visit is required. Some states may require a synchronous (live video) initial visit with your licensed provider before a prescription can be issued.
Some patients may be interested in lower-dose GLP-1 treatment based on tolerability, goals, or provider guidance. Dosing decisions are always made by an independent licensed provider after reviewing your health history, medications, and risk factors. Lower-dose GLP-1 treatment may be considered when clinically appropriate. It is not suitable for everyone, and results vary.
Yes. There are no long-term commitments or cancellation fees. Cancel by emailing members@openwaterrx.com, calling (941) 315-5217 Mon–Fri 9 AM–5 PM ET, or through your patient portal. Once medication for that month has been ordered, that month's charge is not refundable.
Start with clarity.
Continue with guidance.
Complete your online intake and see whether GLP-1 treatment may be appropriate for you. A licensed provider reviews every case.
Treatment determined by licensed providers. Not all patients qualify. Availability and care process may vary by state.
Patients also viewed
Compare Programs
Full side-by-side: mechanism, clinical data, pricing, and patient profiles.
Compare now →
Pricing & Cost
Full pricing breakdown. Semaglutide from $249/mo, tirzepatide from $339/mo.
See pricing →
Am I Eligible?
Check your eligibility for a GLP-1 program. Availability varies by state.
Check eligibility →
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